Chlorhexidine Shampoo with spherulites for dogs.
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Continue to use PYODERM S until the pyoderma has fully resolved and all underlying causes (such as contact allergy or FAD) have been treated or controlled. Once the skin has returned to normal, PYODERM S can be replaced by a gentle cleansing shampoo such as EPISOOTHE® .
In dogs with chronic pyometra or in cases where the underlying aetiology cannot be fully controlled (such as dust mite allergy), it may be necessary to continue using PYODERM S as maintenance shampoo, to prevent the overgrowth of bacteria and yeast and repeated outbreaks of pyoderma.
In trials, PYODERM S was shown to have equivalent activity to a shampoo containing 2%chlorhexidiine and 2% miconazole against malassezia. In this specific formulation and at a concentration of 3% chlorhexidine has been shown to have good activity against malassezia. In vitro Malassezia counts were much reduced after 2 and 4 minutes of exposure and no organisms survived for 8 minutes, demonstrating the rapid antibacterial and antifungal activity of PYODERM S.
The spherulites in PYODERM S are non-ionic. This means that they are not charged and so diffuse through into the cells of the epidermis (which is slightly positively charged) carrying the active ingredient (Chlorhexidine) with them. This helps the active ingredient penetrate into the epidermis where problem is. This is different to our other spherulited products that contain cationic spherultes. Cationic spherulites negatively charged and bind to the hairs and skin surface, holding the active ingredient in place.
The ingestion of a moderate amount of this shampoo would be expected to have no adverse effects, however it is recommended that you do not allow dogs to ingest this product.
Is indicated for the treatment of both bacterial and fungal pyoderma, whether they occur in combination or alone. SEBAZOLE® can be used for fungal skin conditions caused by Malassezia that has an associated seborrhoea and also as an aid in the treatment of fungal overgrowth involving Microsporum spp and Trichophyton spp.