NITROMEC® INJECTION fluke and roundworm treatment for cattle

For the treatment and control of nitroxynil, ivermectin and clorsulon sensitive strains of internal and external parasites of cattle, and triclabendazole resistant strains of early immature (including 2-week old stages), immature and adult liver fluke.

  • Beef Cattle
  • Australian made
    Australian made


  • Outstanding control of liver fluke, including the damaging 2-week old early immature stage
  • Controls triclabendazole resistant strains of liver fluke
  • Synergised combination of nitroxynil and clorsulon
  • Worlds first triple combination injection for cattle
  • Contains ivermectin for broad spectrum control of internal and external parasites
  • Easy to use subcutaneous injection


Areas where liver fluke is found, typically throughout south-eastern Australia generally where rainfall is 600mm or more or in drier areas where irrigation channels are accessible by livestock. This includes south-eastern Queensland, eastern New South Wales, most of Victoria and parts of Tasmania and south-eastern South Australia.

Treatment Timings

  • Autumn Treatment (compulsory)
    7 – 10 days following the first frost. Designed to clean out the fluke prior to the stresses of winter.
  • Spring treatment (compulsory)
    Break the liver fluke lifecycle by removing any fluke that have survived winter. Prevents the contamination of pasture with fluke eggs as temperatures warm up. This treatment should occur prior to the spring break.
  • Summer / early Autumn (tactical)
    Recommended for areas with extended periods of warm conditions. Ideal timing is January or February treatment to suppress fluke numbers.
  • Mid winter treatment (tactical)
    For areas where fluke infection can continue all through the year such as warm coastal areas a mid winter treatment may also be necessary.


  • The strength of synergy
    NITROMEC INJECTION has been developed by Virbac as the world’s first triple combination injection for cattle. It contains a combination of nitroxynil, clorsulon and ivermectin where the combination of nitroxynil and clorsulon provides proven synergistic activity against liver fluke. This synergy makes nitromec one of only two products proven to provide 99% efficacy against two week old early immature stages. The only other product with an approved label claim specifically for the control of two week old liver fluke is Virbac’s FLUKAZOLE® C PLUS SELENIUM.

  • Control of roundworms
    NITROMEC INJECTION offers excellent control of ivermectin-sensitive gastrointestinal roundworms and lungworm.

  • Control of external parasites
    NITROMEC INJECTION controls sucking lice and cattle tick and aids in the control of biting lice and mites.

  • Drench rotation option
    The effective life of drenches can be extended by rotating drench families to slow the onset of drench resistance. NITROMEC INJECTION offers an excellent alternative to triclabendazole drenches for liver fluke control.


  • Nitroxynil (as eglumine): 340g/L
  • Clorsulon: 67g/L
  • Ivermectin: 6.7g/L


NITROMEC INJECTION is given subcutaneously at the recommended dose rate of 1.5mL/50kg bodyweight.

Bodyweight Dose Volume Cattle Treated
(kg) (mL) 1L 2.5L
50-75 2.25 444 1111
76-100 3 333 833
101-150 4.5 222 555
151-200 6 166 416
201-250 7.5 133 333
251-300 9 111 277
310-350 10.5 95 238
351-400 12 83 208
401-450 13.5 74 185
451-500 15 66 166
501-550 16.5 60 151
551-600 18 55 138
601-650 19.5 51 128

Animals in excess of 650kg dosed at 1.5mL/50kg


  • Meat: 56 days (calves born to cows that have been treated with NITROMEC INJECTION during pregnancy must not be slaughtered for human consumption for 56 days after treatment of the dam).
  • Milk: Do not use in cattle which are producing milk or may in the future produce milk where the milk or milk products may be used for human consumption.
  • ESI: 120 days. Do not use less than 120 days before slaughter for export. Calves born to cows that have been treated with NITROMEC INJECTION during pregnancy, must no be slaughtered for export for 120 days after the treatment of the dam.


Store below 30°C (room temperature). Store bottle in outer packaging to protect from light.


Liquid: 1L and 3 x 1L Multipack

Download product SDS 


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