NITROFLUKE® INJECTION fluke treatment for cattle

For the treatment and control of nitroxynil and clorsulon sensitive strains and triclabendazole resistant strains of early immature (including 2-week old stages), immature and adult liver fluke (Fasciola hepatica) in cattle.

  • Beef Cattle
  • Australian made
    Australian made


  • Synergised combination of nitroxynil and clorsulon
  • Outstanding control of liver fluke, including the damaging 2-week old early immature stage
  • Controls triclabendazole resistant strains of liver fluke
  • Easy to use subcutaneous injection


Areas where liver fluke is found, typically throughout south-eastern Australia generally where rainfall is 600mm or more or in drier areas where irrigation channels are accessible by livestock. This includes south-eastern Queensland, eastern New South Wales, most of Victoria and parts of Tasmania and south-eastern South Australia.

Treatment Timings

  • Autumn Treatment (compulsory)
    7 – 10 days following the first frost. Designed to clean out the fluke prior to the stresses of winter.
  • Spring treatment (compulsory)
    Break the liver fluke lifecycle by removing any fluke that have survived winter. Prevents the contamination of pasture with fluke eggs as temperatures warm up. This treatment should occur prior to the spring break.
  • Summer / early Autumn (tactical)
    Recommended for areas with extended periods of warm conditions. Ideal timing is January or February treatment to suppress fluke numbers.
  • Mid winter treatment (tactical)
    For areas where fluke infection can continue all through the year such as warm coastal areas a mid winter treatment may also be necessary.


  • The strength of synergy (control 2 week old fluke)
    NITROFLUKE INJECTION has been developed by Virbac as a critical management tool in controlling all stages of triclabendazole-resistant liver fluke. It contains a combination of nitroxynil and clorsulon which provides proven synergistic activity against liver fluke. This synergy means NITROFLUKE INJECTION controls all stages of liver fluke down to 2 week old early immature liver fluke. The only other products to do this are Virbac’s NITROMEC® INJECTION and FLUKAZOLE® C PLUS SELENIUM

  • Control of Resistant Fluke
    NITROFLUKE INJECTION controls all stages of fluke providing the only straight Flukacide option for Triclabendazole resistant fluke.

  • Drench rotation option
    The effective life of drenches can be extended by rotating drench families to slow the onset of drench resistance. NITROFLUKE INJECTION offers an excellent alternative to Triclabendazole drenches for liver fluke control.

  • Use with Cydectin Long Acting Injection for Cattle
    NITROFLUKE INJECTION can be used alongside CYDECTIN® LONG ACTING INJECTION FOR CATTLE for best practice broad spectrum worm and fluke control.


  • Nitroxynil (as eglumine): 340g/L
  • Clorsulon: 67g/L


NITROFLUKE INJECTION is given subcutaneously at the recommended dose rate of 1.5mL/50kg bodyweight.

Bodyweight Dose Volume Cattle Treated
(kg) (mL) 1L 2.5L
50-75 2.25 444 1111
76-100 3 333 833
101-150 4.5 222 555
151-200 6 166 416
201-250 7.5 133 333
251-300 9 111 277
301-350 10.5 95 238
351-400 12 83 208
401-500 15 66 166
501-550 16.5 60 151
551-600 18 55 138
601-650 19.5 51 128

Animals in excess of 650kg dosed at 1.5mL/50kg


  • Meat: 70 days (calves born to cows that have been treated with NITROFLUKE INJECTION during pregnancy must not be slaughtered for human consumption for 70 days after treatment of the dam).
  • Milk: Do not use in cattle which are producing milk or may in the future produce milk where the milk or milk products may be used for human consumption.
  • ESI: 140 days. Do not use less than 140 days before slaughter for export. Calves born to cows that have been treated with NITROFLUKE INJECTION during pregnancy, must not be slaughtered for export for 140 days after the treatment of the dam.


Store below 30°C (room temperature). Store bottle in outer packaging to protect from light.


Liquid: 1L and 3 x 1L Multipack

Download product SDS 


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