Shaping the future of animal health

Powerup your drench program with a new class of combination sheep drench

TRIDECTIN™ is a new class of combination drench for sheep including three powerful broad-spectrum actives:

  • Moxidectin;
  • Albendazole; and
  • Levamisole.

It is the only combination sheep drench in Australia to include moxidectin, the most potent mectin.

To incorporate moxidectin in the drench, Tridectin utilises a patented micellar technology to improve stability and absorption. Meaning moxidectin stays stable for longer and is more efficacious than an on-farm mix of the same actives.

TRIDECTIN™ is the only broad-spectrum combination drench in the world to incorporate the following claims:

  • Kills triple resistant worms
  • Kills monepantel resistant worms
  • Kills moxidectin sensitive strains of barber's pole worm and small brown stomach worm for 14 days.

With a wide safety profile, very low meat WHP (7 days) and ESI (17 days); Tridectin is fit for use on any enterprise to help sheep producers kill more worms, keep pastures cleaner for longer; and ultimately improve livestock productivity.


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Product Details


Tridectin is a new class of broad-spectrum combination sheep drench.

Tridectin represents a significant step-change in the technology available for sheep producers to control gastrointestinal worms on their property. 


Kills triple resistant worms

TRIDECTIN is one of very few combination oral drenches that can kill triple resistant worms.

To keep winning the fight against resistance it is important that a worm control program limits the proportion of triple resistant worms on your property.

When you use a drench that does not kill triple resistant worms, you are increasing the proportion of these resistant worms on your property.

This mechanism is illustrated below.

triple resistant worms


Kills worms other drenches can’t

TRIDECTIN™ is the only drench with a registered claim to kill worms resistant to monepantel.

Monepantel is the newest class of broad spectrum active released in Australia for the control of gastrointestinal parasites. By using TRIDECTIN™ you are also helping protect the status of all actives that still work on your property.


Kills for longer than any other oral combination drench

TRIDECTIN™ keeps working after your sheep have left the yards and returned to a paddock. This is particularly important during high worm burden seasons or where a low risk paddock cannot be found for the livestock.

Persistent activity reduces the need for additional drenching. In turn, this will help limit the development of resistance because frequent drenching is a known mechanism for resistance selection.


Registration trials against susceptible and multi-resistant worms

TRIDECTIN versus Abamectin Triple against resistant strain of small brown stomach worm TRIDECTIN versus 4-Way Drench


TRIDECTIN versus Abamectin Triple TRIDECTIN versus Monepantel against monepantel resistant worms



Tridectin includes three broad spectrum actives:

  • Moxidectin
  • Albendazole
  • Levamisole

Each of these actives works differently against gastrointestinal worms of sheep. Combining actives with different modes of action is an important requirement to ensure that your worm control program remains viable.


Tomorrows Chemistry for Today’s Parasites

Moxidectin and levamisole are not normally compatible and are therefore difficult to stabilise together in a formulation. To overcome this challenge, Tridectin is formulated via a patented method utilising micellar technology. Micelles are formed by using surfactants in the formulation. Surfactants are organic compounds that contain both a water-insoluble (or oil-soluble-tail) component and a water-soluble component (head).





TRIDECTIN is the only combination drench to include moxidectin.

Why is that important?

  • Moxidectin is strongly lipophilic: this means it attaches to the fat and is gradually released thereby delivering a sustained action.
  • Moxidectin is a very small molecule: the small size of the molecule means that it can rapidly pass through membranes and into the parasite reaching high concentrations much faster.
  • Moxidectin has less affinity for ABC transporters: Parasite cells have transporters which remove foreign materials and waste products from them. Compared to other mectins, moxidectin is less attracted to these transporters. This means that moxidectin stays in the cell for longer at a higher concentration.

    A lack of affinity for ABC transporters is also a reason why moxidectin is slower to develop resistance compared to the avermectins.

avermectin vs moxidectin


Moxidectin is more effective because it enters worm cells more rapidly and reaches higher concentrations faster and is retained in the parasite for longer than the avermectins.


Committed to Australia

Australian madeVirbac is the only animal health company in Australia that develops and manufactures sheep drench products locally with investment from a large international parent company.

Virbac Australia employs nearly 300 personnel across Australia. We have 3 manufacturing plants one located in Crookwell, regional NSW and the other two in Penrith and Macquarie Park, Sydney.

Virbac continues to invest in Australia and has several new livestock products proceeding through our research and development pipeline.


A heritage you know and trust

Virbac are the makers of the sheep and cattle brand Cydectin. TRIDECTIN™ represents an evolution from the powerful single active represented by Cydectin to a powerful new class of combination drench for the market.

Livestock producers have made Cydectin their most trusted agricultural brand; TRIDECTIN™ will extend on that trust and help keep your worm control program viable into the future.


When To Use

Tridectin is suitable for any occasion

TRIDECTIN™ is suitable to use as a drench in the following circumstances:

  • Pre-lambing treatment where sustained activity beyond 14 days is not required;
  • Weaner treatment where tape worm control is not required;
  • Prime lamb drench – 17 days is the best ESI of any comparable product; and
  • Summer drench – ideally to be used as a first Summer drench where there is likely to be a mixture of worm species present.

For more information on drenching practices relevant to your district visit

Points to remember

Tridectin is suitable for all classes of stock over 12kg weight but it is important to exercise care in handling:

  • Weak, pregnant and young animals to avoid unnecessary stress.
  • Avoid yarding animals off feed overnight, and ensure animals have access to water when yarded prior to drenching.
  • Recommended dose should not be exceeded, except under veterinary supervision.
  • Doses of three or more times the recommended dose can cause symptoms of levamisole toxicity; hence bodyweights and doses should be determined accurately.
  • Dehydrated animals may be more susceptible to toxicity.


TRIDECTIN™ is given orally at the recommended dose rate of 1mL/5kg

Animals in excess of 75 kg bodyweight to be dosed at 1mL/5kg


  • MEAT: DO NOT USE less than 7 days before slaughter for human consumption.
  • MILK: DO NOT USE in sheep which are producing or may in the future produce milk or milk products for human consumption.


  • EXPORT SLAUGHTER INTERVAL (ESI): DO NOT USE less than 17 days before slaughter for export.


Share Your Positive Story

Running a farm can be one of the most rewarding and exciting career choices a person can choose to take on.  You are in charge and take an active interest in driving the profitability of your business so that it remains sustainable for you and future generations. 

You continue to run this business when others would have given in. Others find the vagaries of market and seasonal conditions too tough to handle.  Others relent under the loneliness and demands of running a 24/7 business.

But you don’t, you tough it out.  You take a positive attitude and despite the challenges thrown your way, you keep winning.

You continue to win because you make smart decisions. You are progressive and adopt the latest technology and strive towards standards and achievements others consider impossible.

There is a fountain of positivity in the agricultural community ready to be tapped into and we want to help share that with others, so that they might learn from your experiences.

Positivity breeds positivity: so please share your positive story and share a photo of what you love about working in agriculture.

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